Long Term Effects of Sleep Deprivation

Sleep deprivation is a commonplace occurrence in modern culture. Every day there seems to be twice as much work and half as much time to complete it in.

After periods of extended wakefulness or reduced sleep neurons may begin to malfunction, visibly effecting a person’s behavior. Some organs, such as muscles, are able to regenerate even when a person is not sleeping so long as they are resting. This could involve lying awake but relaxed within a quite environment. However, in sleep deprived subjects there is no activity within this region.

Effects of sleep deprivation

The effects of this inactivity can be observed by the slurred speech in subjects who have gone for prolonged periods with no sleep.

Even severely sleep deprived people are still able to perform to some degree on a verbal learning test. This implies that some other area of the brain must become active to compensate for the loss of temporal lobe functioning. In fact, activity can be seen in the parietal lobe that is not present during verbal learning tests using rested subjects.

Greater activity within this region corresponded to better performance by subjects in research studies. Still, sleep deprived people do not perform as well on these tests as do fully rested subjects.

One possible reason for the poorer performance after missing sleep, aside from unregenerated neurons, could be the fact that since the parietal lobe is not usually used to performing tasks such as these it is not as adept at carrying them out. Judgment, impulse control, attention, and visual association have all been related to this region of the cerebral cortex. If the neurons composing the I-function become too taxed then the picture in the head that the I-function produces may be more dissimilar from reality than usual. The neurons, under pressure to continue functioning but unable to perform optimally, create an image useful enough for a person to see most of his or her surroundings.

Metabolic activity in the prefrontal cortex can drop as much as eleven percent after a person has missed sleep for only twenty four hours. As a person loses more sleep or continues to receive less-than-adequate amounts of sleep the neurons become even more taxed and the I-function may begin to generate even less coherent images possibly resulting in temporary insanity.

Another piece of evidence supporting the location of the I-function is that mammals have REM sleep whereas cold-blooded animals do not and mammals have a neocortex, located within the prefrontal cortex, while cold-blooded animals do not. REM sleep stimulates areas of the brain used for learning and memory. When a person is taught a new skill his or her performance does not improve until he or she receives at least eight hours of sleep. Without them new synapses may not be able to be formed, thus limiting the amount of information a sleep-deprived individual can maintain.

One of the possible side effects of a continued lack of sleep is death. Usually this is the result of the fact that the immune system is weakened without sleep. The body also decreases the amount of growth hormone produced. The ability of the body to metabolize sugar declines, turning sugar into fat. Since different regions of the brain rest during different stages of the sleep cycle, sleep cannot be cut short. In fact, if the brain does not receive a break it will soon begin to shut down for periods of microsleep. This is essentially several seconds of actual sleep; delta waves that interrupt the regular EEG of an awake person thereby impairing his or her continuity of cognitive function.

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